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Please contact us through twitter (@ultraconserved) if you are interested in helping and/or post an issue on github for the respective package.

Our main code repository for analyzing data collection from UCE loci.

Order enrichment kits from MYcroarray » The linked FASTA file (ZIP archive) contains probe sequences (120 nt) designed for synthesis as part of a Agilent Sure Select or Mycro Array My Bait target enrichment kit.

We used these probes for our analysis of early diverging teleosts.

Frequently asked questions » Faircloth BC, Branstetter MG, White ND, Brady SG. Target enrichment of ultraconserved elements from arthropods provides a genomic perspective on relationships among Hymenoptera. All probes are available under a CC0 license, thus freely available for you to use, without restriction.

We have several larger probes sets in the works for fishes, and we are also working on optimizing probe sets based on their capture success, phylogenetic utility, etc. You can now buy this probe set direct from MYcroarray in the form of a capture kit.

MYcroarray has even made a discounted "pilot" sized kit available for labs who want to do some test enrichments.

2007) identified additional regions of high conservation.

We have discovered (see Citations) that we can collect data from UCEs and the DNA adjacent to UCE locations (flanking DNA), and that these data are useful for reconstructing the evolutionary history and population-level relationships of many organisms. 2004) and we generally assume that UCEs must be important by the very nature of their near-universal conservation across extremely divergent taxa.

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